Invasive lobular carcinoma ILC is a type of breast cancer that starts in the lobules of your breast, where milk is produced. It is also a bilateral cancer, which means it can affect both breasts. Here is what you need to know about invasive lobular carcinoma, including prevalence, symptoms, causes, treatment, and how to cope. ILC is the second most common type of breast cancer after invasive ductal carcinoma cancer that begins in the milk-carrying ducts and spreads beyond it.
Invasive Lobular Carcinoma
Understand Your Breast Cancer Diagnosis | Types of Breast Cancer
Metrics details. Invasive lobular and ductal carcinomas differ with respect to risk factors. Invasive lobular carcinoma is more strongly associated with exposure to female hormones, and therefore its incidence is more subject to variation. Similarly, invasive lobular carcinoma is more strongly associated with early menarche, late menopause and late age at first birth. CDH1 , the gene coding for the E-cadherin adhesion protein, is of special interest as mutations are associated with invasive lobular carcinoma, but never with ductal carcinoma. It was initially known as the main susceptibility gene for gastric cancer of the diffuse type, but the excess of breast cancers of the lobular type in CDH1 families led researchers to identify it also as a susceptibility gene for invasive lobular carcinoma. Invasive breast cancer is a heterogeneous disease of two main histological types, invasive ductal carcinoma IDC and invasive lobular carcinoma ILC , IDC being by far the most common.
Understanding a Breast Cancer Diagnosis
Not all breast cancers are the same. Understand what type of breast cancer you have and how it differs from other types of breast cancer. Once you've been diagnosed with breast cancer, your doctor will review your pathology report and the results of any imaging tests to understand the specifics of your tumor.
Sound scary? It is to tumours, as this weakness is proving to be an efficient way to eliminate specific cancer cells without harming healthy cells. Our cells have thousands of different genes coding for proteins that work together to keep cells healthy.